Guidelines to Evaluate Human Observational Studies for Quantitative Risk Assessment

Guidelines to Evaluate Human Observational Studies for Quantitative Risk Assessment

BACKGROUND Careful evaluation of the quality of human observational studies (HOS) is required to assess the suitability of HOS for quantitative risk assessment (QRA). In particular, the quality of quantitative exposure assessment is a crucial aspect of HOS to be considered for QRA. OBJECTIVE We aimed to develop guidelines for the evaluation of HOS for QRA and to apply these guidelines to case...

Exposure Assessment to Environmental Pollutants in Human Health Risk Assessment Studies; Overview on New Approaches

Background & objectives: Because of human exposure to various environmental risk factors during the lifetime, the actual exposure estimation has been considered as one of the most important challenges for researchers and decision makers. Considering the contribution of environmental risk factors in the burden of diseases, this study aimed to provide new approaches in exposure assessment filed b...

Quantitative Assessment of Muscle Fatigue for FES Research Studies

Background: Muscle fatigue is an important issue in neuromuscular rehabilitation. Better control of this phenomenon would result in better prevention of its consequent physiological damages.Objective: To provide a mathematical representation of muscle fatigue as a function of time.Methods: We conducted this study by combining the EMG-based estimation methods of muscle activation with the availa...

A quantitative risk assessment model to evaluate effective border control measures for rabies prevention

Border control is the primary method to prevent rabies emergence. This study developed a quantitative risk model incorporating stochastic processes to evaluate whether border control measures could efficiently prevent rabies introduction through importation of cats and dogs using Taiwan as an example. Both legal importation and illegal smuggling were investigated. The impacts of reduced quarant...

Guidelines for Carcinogen Risk Assessment